RARECHEM AH PB 0129
3-Chloro-4-fluorophenylboronic acid
CAS: 144432-85-9
Molecular Formula: C6H5BClFO2
RARECHEM AH PB 0129 - Names and Identifiers
RARECHEM AH PB 0129 - Physico-chemical Properties
| Molecular Formula | C6H5BClFO2 |
| Molar Mass | 174.37 |
| Density | 1.41±0.1 g/cm3(Predicted) |
| Melting Point | 242-247 °C (lit.) |
| Boling Point | 306.0±52.0 °C(Predicted) |
| Appearance | Solid |
| Color | Off-white to faintly orange |
| BRN | 7369789 |
| pKa | 7?+-.0.10(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| MDL | MFCD00051800 |
| Physical and Chemical Properties | Storage Conditions: recigerator (4 ℃) WGK Germany:3 |
RARECHEM AH PB 0129 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29163990 |
| Hazard Class | IRRITANT |
RARECHEM AH PB 0129 - Introduction
acid is an organic compound with the chemical formula C6H4BClF2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: acid is a white solid.
2. Melting Point: about 170 ° C.
3. Solubility: Soluble in organic solvents such as chloroform, ether, dichloromethane, etc., insoluble in water.
4. Chemical properties: acid is a weak acid, which can react with alkali.
Use:
1. Chemical reagent: acid can be used as an important reagent in organic synthesis, such as transition metal catalyzed reactions.
2. Preparation of other compounds: It can be used to synthesize organic compounds with pharmaceutical activity or pesticide activity.
Method:
The preparation method of Ni acid can be carried out by aromatic iodination reaction. First, boric acid and iodine were added to the reaction system in the presence of aromatic compound 4-chloro -3-fluorobenzyl alcohol, and the product acid was obtained by heating reaction.
Safety Information:
1. acid powder can cause irritation to eyes, skin and respiratory tract, and should be washed in time after contact.
2. Wear appropriate protective equipment such as chemical protective gloves, goggles and protective clothing during operation.
3. Avoid mixing with oxidants, acids, alkalis and other substances to prevent dangerous reactions.
4. When storing, acid should be placed in a sealed container and kept away from fire and heat sources.
when using or handling acid, please follow the relevant safety procedures and be cautious in handling drugs.
Nature:
1. Appearance: acid is a white solid.
2. Melting Point: about 170 ° C.
3. Solubility: Soluble in organic solvents such as chloroform, ether, dichloromethane, etc., insoluble in water.
4. Chemical properties: acid is a weak acid, which can react with alkali.
Use:
1. Chemical reagent: acid can be used as an important reagent in organic synthesis, such as transition metal catalyzed reactions.
2. Preparation of other compounds: It can be used to synthesize organic compounds with pharmaceutical activity or pesticide activity.
Method:
The preparation method of Ni acid can be carried out by aromatic iodination reaction. First, boric acid and iodine were added to the reaction system in the presence of aromatic compound 4-chloro -3-fluorobenzyl alcohol, and the product acid was obtained by heating reaction.
Safety Information:
1. acid powder can cause irritation to eyes, skin and respiratory tract, and should be washed in time after contact.
2. Wear appropriate protective equipment such as chemical protective gloves, goggles and protective clothing during operation.
3. Avoid mixing with oxidants, acids, alkalis and other substances to prevent dangerous reactions.
4. When storing, acid should be placed in a sealed container and kept away from fire and heat sources.
when using or handling acid, please follow the relevant safety procedures and be cautious in handling drugs.
Last Update：2024-04-09 21:01:54
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